منابع مشابه
Relevance for clinical practice
OBJECTIVE To review evidence from literature on type 2 diabetes pertinent to physical activity and diet and lifestyle modification, and to determine the relevance of this evidence to clinical practice. QUALITY OF EVIDENCE Direct (level I) evidence supports interventions for physical activity and diet modification for primary prevention and management of type 2 diabetes. Few studies examine the ...
متن کاملClinical Relevance of Adipokines
The incidence of obesity has increased dramatically during recent decades. Obesity increases the risk for metabolic and cardiovascular diseases and may therefore contribute to premature death. With increasing fat mass, secretion of adipose tissue derived bioactive molecules (adipokines) changes towards a pro-inflammatory, diabetogenic and atherogenic pattern. Adipokines are involved in the regu...
متن کاملOncogenes: clinical relevance.
The last 10 years have seen something of a revolution in experimental carcinogenesis, sparked by the discovery of oncogenes [1-3]. The first such gene and most of the ones that followed [1] have been isolated as part of the genome of a tumor-inducing retrovirus. Mostly obtained from birds and mice, these viral oncogenes are nearly identical to genes present in normal cells and, because of their...
متن کاملImportance of clinical relevance in clinical trials.
To the Editor:—We read with interest the article by Santoni et al. Maintaining manual in-line stabilization for direct laryngoscopy in patients with known or suspected cervical spine injury is a practice which would benefit from further research. However, we believe the protocol design in this study has limited the clinical relevance of the data generated. The authors designed a prototype press...
متن کاملClinical Relevance of Molecular Microbiology
Molecular methods for the detection and characterization of microorganisms have transformed diagnostic microbiology. Detection of microorganisms was previously laborious and time taking by conventional microbiological methods but now more rapid detection by molecular methods is possible for pathogens of public health importance. Detection of antimicrobial resistance genes and their characteriza...
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ژورنال
عنوان ژورنال: Deutsches Aerzteblatt Online
سال: 2010
ISSN: 1866-0452
DOI: 10.3238/arztebl.2010.0039b